Plakoglobin Antibody / Gamma Catenin
Plakoglobin is a major cytoplasmic component of both desmosomes and adherens junctions, and is the only known constituent common to submembranous plaques in both of these structures, which are located at the intercalated disc (ICD) of cardiomyocytes. It links cadherins to the actin cytoskeleton. Plakoglobin binds to conserved regions of desmoglein and desmocollin at intracellular catenin-binding sites to assemble desmosomes. [Wiki]
Product Specifications
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 0.1-0.2 µg/mL for 30 min at RT
UniProt
P14923
Host
Mouse
Reactivity
Human
Immunogen
Recombinant human protein was used as the immunogen for the Plakoglobin antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
CTNG/1483
Applications
IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Reconstitution
Store the Plakoglobin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This Plakoglobin antibody is available for research use only.
Storage Conditions
Store the Plakoglobin antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Applications Notes
Location
Cell surface, cytoplasmic, cell junctions
Image Legend
Documents
Frequently Asked Questions
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