IgG Antibody Cocktail
This mAb is specific to heavy chain of IgG and shows minimal cross-reaction with heavy chains of other immunoglobulins. It is reactive with all subclasses of gamma heavy chain (IgG1, IgG2a, IgG2b, IgG3) . The most common feature of plasmacytomas, and certain non-Hodgkin's lymphomas is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant. Ab-3 is superb for staining of formalin-fixed tissues.
Product Specifications
CAS Number
9007-83-4
Specifications
Flow cytometry: 1ug/10^6 cells, Immunofluorescence: 0.5-1 µg/mL, Immunohistochemistry (FFPE) : 0.5-1 µg/mL for 30 min at RT
UniProt
P01857, P01859, P01860, P01861
Host
Mouse
Reactivity
Human
Immunogen
Purified human IgG was used as the immunogen for this IgG antibody.
Clonality
Monoclonal
Isotype
IgG1,IgG2a
Clone
IG217 + IG266
Applications
FACS, IF, IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Reconstitution
Store the IgG antibody cocktail at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This IgG antibody cocktail is available for research use only.
Storage Conditions
Store the IgG antibody cocktail at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Location
Cytoplasm, Cell Surface and Secreted
Image Legend
IHC: Formalin-fixed, paraffin-embedded human tonsil stained with IgG antibody (IG217 + IG266)
Documents
Frequently Asked Questions
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