Cytokeratin 19 Antibody Cocktail
This mAb reacts with the rod domain of human cytokeratin-19 (CK19), a polypeptide of 40kDa. CK19 is expressed in sweat gland, mammary gland ductal and secretory cells, bile ducts, gastrointestinal tract, bladder urothelium, oral epithelia, esophagus, and ectocervical epithelium. Anti-CK19 reacts with a wide variety of epithelial malignancies including adenocarcinomas of the colon, stomach, pancreas, biliary tract, liver, and breast. Perhaps the most useful application is the identification of thyroid carcinoma of the papillary type, although 50%-60% of follicular carcinomas are also labeled. Anti-CK19 is a useful marker for detection of tumor cells in lymph nodes, peripheral blood, bone marrow and breast cancer.
Product Specifications
CAS Number
9007-83-4
Specifications
UniProt
P08727
Host
Mouse
Reactivity
Human
Immunogen
MCF-7 cells (A53-B/A2) and human mammary epithelial organoids (BA17) were used as the immunogen for this Cytokeratin 19 antibody cocktail.
Clonality
Monoclonal
Isotype
IgG1 k,IgG2a λ
Clone
A53-B/A2.26 + BA17
Applications
IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
Prediluted in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide; *For IHC use only*
Reconstitution
Store the Cytokeratin 19 antibody cocktail at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This Cytokeratin 19 antibody cocktail is available for research use only.
Storage Conditions
Store the Cytokeratin 19 antibody cocktail at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
Prediluted in 1X PBS, 0.1 mg/mL BSA (US sourced), 0.05% sodium azide; *For IHC use only*
Location
Cytoplasmic
Image Legend
IHC: Formalin-fixed, paraffin-embedded human colon carcinoma stained with Cytokeratin 19 antibody (A53-B/A2.26 + BA17) .
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