C-Myb Antibody
The highly leukemogenic avian retrovirus E26 contains two oncogenes, v-Myb and v-Ets, which are expressed together as a fusion protein. The cellular homolog of v-Myb, designated c-Myb, encodes a transcription factor. Deletion or disruption of a negative regulatory domain mapping within the carboxy-terminal domain of c-Myb results in enhanced transactivating capacity and in parallel, leads to activation of its ability to transform hemopoietic cells. c-Myb is expressed preferentially, but not exclusively, in immature hemopoietic cells and its expression decreases as cells differentiate.
Product Specifications
CAS Number
9007-83-4
Specifications
ELISA: 2-4 µg/mL (order BSA/azide-free format)
UniProt
P01104
Host
Mouse
Reactivity
Human
Immunogen
Amino acids 119-135 (RRKVEQEGYPQESSKAG) from the human protein were used as the immunogen for this c-Myb antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
MYB286
Applications
ELISA
Purity
Protein G affinity chromatography
Format
Purified
Buffer
1 mg/ml in 1X PBS; BSA free, sodium azide free
Reconstitution
Store the c-Myb antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This c-Myb antibody is available for research use only.
Storage Conditions
Store the c-Myb antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Product Datasheet
https://www.nsjbio.com/tds-pdf/c-myb-antibody-myb286-v3123
Formulation
1 mg/mL in 1X PBS; BSA free, sodium azide free
Applications Notes
The optimal dilution of the c-Myb antibody for each application should be determined by the researcher.
Location
Nuclear
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
