HepPar1 Antibody
Hepatocyte Paraffin 1 or HepPar-1 localizes to the mitochondria of hepatocytes. It is a sensitive marker for distinguishing hepatocellular carcinomas (HCC) from other metastatic carcinomas as well as cholangio-carcinomas. HCC s occur primarily in the stomach, but they are also found in many other organs. The Hepatocyte Specific Antigen may also be a useful marker for intestinal metaplasia. Reportedly, strong expression of the Hepatocyte Specific Antigen correlates with smaller tumor size and longer patient survival. Occasionally, Hepatocyte Specific Antigen is also found in gastric carcinomas as well as in a few other non-hepatic tumors.
Product Specifications
CAS Number
9007-83-4
Specifications
Immunofluorescence: 0.5-1 µg/mL, Immunohistochemistry (FFPE) : 0.25-0.5 µg/mL for 30 min at RT
UniProt
Not Known
Host
Mouse
Reactivity
Human
Immunogen
Extract of a formalin-fixed, rejected-allograft of a human liver was used as the immunogen for the HepPar1 antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
HepPar1
Applications
IF, IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Reconstitution
Store the HepPar1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This HepPar-1 antibody is available for research use only.
Storage Conditions
Store the HepPar1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Location
Finely granular cytoplasmic
Image Legend
IHC: Formalin-fixed, paraffin-embedded human hepatocellular carcinoma stained with HepPar1 antibody (clone HepPar1) .
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