HPV-16 L1 Antibody
Reacts with a protein of 57kDa, identified as the L1 protein of human papilloma virus type 16 (HPV-16) . It is the major capsid protein of HPV-16. Infection with specific types of HPV has been associated with an increased risk of developing cervical neoplasia. HPV types 6 and 11 have been associated with relatively benign diseases such as genital warts but types 16 and 18 are strongly associated with cervical, vaginal, and vulvar malignancies. The antibody reacts very strongly with formalin-fixed, paraffin-embedded tissues containing HPV-16 or -33; very weak reactions were occasionally observed with biopsy specimens or smears containing HPV-6 or HPV-11. It cross-reacts with HPV37.
Product Specifications
CAS Number
9007-83-4
Specifications
Flow cytometry: 5ul per test per one 10^6 cells in 0.1ml or 5ul per 100ul of whole blood, Immunofluorescence: 1-2 µg/mL
UniProt
P03101
Host
Mouse
Reactivity
HPV-16
Immunogen
Human papilloma virus type 16, major capsid protein L1, was used as the immunogen for the HPV-16 L1 antibody.
Clonality
Monoclonal
Isotype
IgG2a κ
Clone
HPV16L1/1058
Applications
FACS, IF
Purity
Protein G affinity chromatography
Format
CF488 Conjugate
Buffer
500 ul at 0.1 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Store the HPV-16 L1 antibody at 2-8oC, protected from light.
Limitations
This HPV-16 L1 antibody is available for research use only.
Storage Conditions
Store the HPV-16 L1 antibody at 2-8°C, protected from light.
Formulation
500 ul at 0.1 mg/mL with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide
Applications Notes
Optimal dilution of the HPV-16 L1 antibody should be determined by the researcher.
Location
Nuclear
Frequently Asked Questions
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