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IPO38 Antibody (Proliferation Marker)

Recognizes a protein of 14-16kDa, which is a novel nuclear antigen of proliferating cells. IPO-38 antigen is present in the nuclei of proliferating cells such as Hodgkin s disease and non-Hodgkin s lymphomas, different forms of leukemias, breast and colorectal carcinomas, and PHA-stimulated lymphocytes. It is not expressed in the cells of non-stimulated lymphocytes and granulocytes. IPO-38 can be a useful marker of cell proliferation during monitoring of tumor progression.

Product Specifications

CAS Number

9007-83-4

Specifications

The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

UniProt

Not Known

Host

Mouse

Reactivity

Human, Mouse, Rat

Immunogen

Spleen cells from a patient with hairy cell leukemia were used as the immunogen for the IPO38 antibody.

Clonality

Monoclonal

Isotype

IgM k

Clone

SPM515

Applications

IHC-P

Purity

PEG precipitation

Format

Purified

Buffer

Prediluted in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide; *For IHC use only*

Reconstitution

Store the IPO38 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Limitations

This IPO38 antibody is available for research use only.

Storage Conditions

Store the IPO38 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .

Formulation

Prediluted in 1X PBS, 0.1 mg/mL BSA (US sourced), 0.05% sodium azide; *For IHC use only*

Location

Nuclear

Image Legend

IHC: Formalin-fixed, paraffin-embedded human tonsil stained with IPO38 antibody (SPM515) .

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