IPO38 Antibody (Proliferation Marker)
Recognizes a protein of 14-16kDa, which is a novel nuclear antigen of proliferating cells. IPO-38 antigen is present in the nuclei of proliferating cells such as Hodgkin s disease and non-Hodgkin s lymphomas, different forms of leukemias, breast and colorectal carcinomas, and PHA-stimulated lymphocytes. It is not expressed in the cells of non-stimulated lymphocytes and granulocytes. IPO-38 can be a useful marker of cell proliferation during monitoring of tumor progression.
Product Specifications
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 min at RT
UniProt
Not Known
Host
Mouse
Reactivity
Human, Mouse, Rat
Immunogen
Spleen cells from a patient with hairy cell leukemia were used as the immunogen for the IPO38 antibody.
Clonality
Monoclonal
Isotype
IgM k
Clone
SPM515
Applications
IHC-P
Purity
PEG precipitation
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Reconstitution
Store the IPO38 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This IPO38 antibody is available for research use only.
Storage Conditions
Store the IPO38 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Location
Nuclear
Image Legend
IHC: Formalin-fixed, paraffin-embedded human tonsil stained with IPO38 antibody (SPM515) .
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