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IPO38 Antibody (Proliferation Marker)

Recognizes a protein of 14-16kDa, which is a novel nuclear antigen of proliferating cells. IPO-38 antigen is present in the nuclei of proliferating cells such as Hodgkin s disease and non-Hodgkin s lymphomas, different forms of leukemias, breast and colorectal carcinomas, and PHA-stimulated lymphocytes. It is not expressed in the cells of non-stimulated lymphocytes and granulocytes. IPO-38 can be a useful marker of cell proliferation during monitoring of tumor progression.

Product Specifications

CAS Number

9007-83-4

Specifications

Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 min at RT

UniProt

Not Known

Host

Mouse

Reactivity

Human

Immunogen

Spleen cells from a patient with hairy cell leukemia were used as the immunogen for the IPO38 antibody.

Clonality

Monoclonal

Isotype

IgM k

Clone

SPM260

Applications

IHC-P

Purity

PEG precipitation

Format

Purified

Buffer

0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide

Reconstitution

Store the IPO38 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Limitations

This IPO38 antibody is available for research use only.

Storage Conditions

Store the IPO38 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .

Formulation

0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide

Location

Nuclear

Image Legend

IHC: Formalin-fixed, paraffin-embedded human tonsil stained with IPO38 antibody (SPM260) .

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