Rabies Virus Antibody
Reacts with viral glycoprotein of rabies virus strains SAD-Vnukovo and Pitman-Moore. This mAb is useful in detecting rabies virus by ELISA and Western. It is capable of neutralizing rabies virus. Rabies virus (Neurotropic virus) is a member of the Rhabdoviridae family. Rabies is a single stranded, neurotropic, negative sense RNA virus which encodes 5 proteins: a glycoprotein, a nucleoprotein, and three others. The mature virus has a bullet shape, a protein coat, and a lipid envelope. The outer surface of the virus is covered with thumb like glycoprotein projections 5-10 nm long and 3 nm in diameter. The virus averages approximately 780 nm in length. Lipid solvents destroy virus infectivity. Rabies virus is a very successful virus, with a very wide range of hosts. It causes an acute, central nervous system infection, characterized by CNS irritation, followed by paralysis and death. Approximately 50,000 human deaths each year are caused by rabies.
Product Specifications
CAS Number
9007-83-4
Specifications
ELISA (order BSA/sodium azide-free format for coating), Immunofluorescence: 0.5-1 µg/mL
UniProt
Not Applicable
Host
Mouse
Immunogen
Purified virions of SAD-Vnukovo strain followed by Pitman-Moore strain was used as the immunogen for the Rabies Virus antibody.
Clonality
Monoclonal
Isotype
IgG2b κ
Clone
Rab-50
Applications
ELISA, IF
Purity
Protein G affinity chromatography
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Reconstitution
Store the Rabies Virus antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This Rabies Virus antibody is available for research use only.
Storage Conditions
Store the Rabies Virus antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Applications Notes
Optimal dilution of the Rabies Virus antibody should be determined by the researcher.
Location
Virus
Image Legend
SDS-PAGE Analysis of Purified, BSA-Free Rabies Virus Antibody (clone Rab-50) . Confirmation of Integrity and Purity of the Antibody.
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