CD38 Antibody
This mAb reacts with a 45kDa glycopeptide, which is a type II membrane glycoprotein with a transmembrane sequence near the NH2 terminus. CD38 is a type II transmembrane glycoprotein that is present on early B- and T-cell lineages and activated B- and T-cells but is absent from most mature resting peripheral lymphocytes. CD38 is also found on thymocytes, pre-B cells, germinal center B-cells, mitogen-activated T-cells, monocytes and Ig-secreting plasma cells. CD38 is expressed on CD34+ cells. The CD34+CD38- population of hematopoietic stems cells defines the most pluripotent cells (e.g. blast colony forming cells) .
Product Specifications
CAS Number
9007-83-4
Specifications
Flow cytometry: 0.5-1ug/10^6 cells, Immunofluorescence: 1-2 µg/mL
UniProt
P28907
Host
Mouse
Reactivity
Human
Immunogen
The human T cell line CCRF-CEM was used as the immunogen for the CD38 antibody.
Clonality
Monoclonal
Isotype
IgG3 κ
Clone
AT2
Applications
FACS, IF
Purity
Protein G affinity chromatography
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Reconstitution
Store the CD38 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This CD38 antibody is available for research use only.
Storage Conditions
Store the CD38 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Applications Notes
Optimal dilution of the CD38 antibody should be determined by the researcher.
Location
Cell surface, cytoplasm and nucleus
Documents
Frequently Asked Questions
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