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PROTAC CDK9 degrader-4

PROTAC CDK9 degrader-4 is a highly potent and efficacious CDK9 degrader for targeting transcription regulation.

Product Specifications

CAS Number

[2411021-01-5]

Product Name Alternative

BMS 234303-01

UNSPSC

12352005

Target

PROTACs

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/protac-cdk9-degrader-4.html

Purity

99.65

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C(N1CCN(CCCCCC2=CC=CC3=C2CN(C(CC4)C(NC4=O)=O)C3=O)CC1)NC5=CC=C(CNC6=CC(N[C@H](CO)CC)=NC7=C(C(C)C)C=NN67)C=C5

Molecular Formula

C43H56N10O5

Molecular Weight

792.97

References & Citations

[1]Wei D, et al. Discovery of Potent and Selective CDK9 Degraders for Targeting Transcription Regulation in Triple-Negative Breast Cancer. J Med Chem. 2021 Oct 14;64 (19) :14822-14847.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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