Caldesmon Antibody / CALD1 / CAD (HMW)
Recognizes a protein of 150kDa, which is identified as the high molecular weight variant of Caldesmon. Two closely related variants of human caldesmon have been identified which are different in their electrophoretic mobility and cellular distribution. The h-caldesmon variant (120-150kDa) is predominantly expressed in smooth muscle whereas l-caldesmon (70-80kDa) is found in non- muscle tissue and cells. Neither of the two variants has been detected in skeletal muscle. Caldesmon is a developmentally regulated protein involved in smooth muscle and non-muscle contraction.
Product Specifications
CAS Number
9007-83-4
Specifications
UniProt
Q05682
Host
Mouse
Reactivity
Human
Immunogen
Crude human uterus extract was used as the immunogen for the Caldesmon antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
SPM168
Applications
IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
Prediluted in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide; *For IHC use only*
Reconstitution
Store the Caldesmon antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This Caldesmon antibody is available for research use only.
Storage Conditions
Store the Caldesmon antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
Prediluted in 1X PBS, 0.1 mg/mL BSA (US sourced), 0.05% sodium azide; *For IHC use only*
Location
Cytoplasmic
Image Legend
IHC: Formalin-fixed, paraffin-embedded human uterus stained with Caldesmon antibody (clone SPM168) .
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