CAIX Antibody / Carbonic anhydrase IX

Recognizes a glycoprotein identified as carbonic anhydrase IX (CAIX) . Carbonic Anhydrases (CAs) are members of a large family of zinc metallo-enzymes that catalyze the reversible hydration of carbon dioxide. CAs are involved in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption and the formation of aqueous humor, cerebrospinal fluid, saliva and gastric juice. They show extensive diversity in distribution and in their subcellular localization. CA IX is specifically expressed in clear-cell renal carcinomas.

Product Specifications

CAS Number

9007-83-4

Specifications

The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

UniProt

Q16790

Host

Mouse

Reactivity

Human

Immunogen

Recombinant human protein was used as the immunogen for the CAIX antibody.

Clonality

Monoclonal

Isotype

IgG2b κ

Clone

CA9/781

Applications

IHC-P

Purity

Protein G affinity chromatography

Format

Purified

Buffer

Prediluted in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide; *For IHC use only*

Reconstitution

Store the CAIX antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Limitations

This CAIX antibody is available for research use only.

Storage Conditions

Store the CAIX antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .

Formulation

Prediluted in 1X PBS, 0.1 mg/mL BSA (US sourced), 0.05% sodium azide; *For IHC use only*

Location

Cell surface and cytoplasmic

Image Legend

IHC: Formalin-fixed, paraffin-embedded human renal cell carcinoma stained with CAIX antibody (CA9/781) .

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