CAIX Antibody / Carbonic anhydrase IX
Recognizes a glycoprotein identified as carbonic anhydrase IX (CAIX) . Carbonic Anhydrases (CAs) are members of a large family of zinc metallo-enzymes that catalyze the reversible hydration of carbon dioxide. CAs are involved in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption and the formation of aqueous humor, cerebrospinal fluid, saliva and gastric juice. They show extensive diversity in distribution and in their subcellular localization. CA IX is specifically expressed in clear-cell renal carcinomas.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 0.5-1 µg/mL, Immunohistochemistry (FFPE) : 0.5-1 µg/mL for 30 min at RT
UniProt
Q16790
Host
Mouse
Reactivity
Human
Immunogen
Recombinant human protein was used as the immunogen for the CAIX antibody.
Clonality
Monoclonal
Isotype
IgG2b κ
Clone
CA9/781
Applications
WB, IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Reconstitution
Store the CAIX antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This CAIX antibody is available for research use only.
Storage Conditions
Store the CAIX antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Location
Cell surface and cytoplasmic
Image Legend
IHC: Formalin-fixed, paraffin-embedded human renal cell carcinoma stained with CAIX antibody (CA9/781) .
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