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UchL1 Antibody

This mAb reacts with a protein of 20-30kDa, identified as PGP9.5, also known as ubiquitin carboxyl-terminal hydrolase-1 (UchL1) . Initially, PGP9.5 expression in normal tissues was reported in neurons and neuroendocrine cells but later it was found in distal renal tubular epithelium, spermatogonia, Leydig cells, oocytes, melanocytes, prostatic secretory epithelium, ejaculatory duct cells, epididymis, mammary epithelial cells, Merkel cells, and dermal fibroblasts. Furthermore, immunostaining for PGP9.5 has been shown in a wide variety of mesenchymal neoplasms as well. A mutation in PGP9.5 gene is believed to cause a form of Parkinson's disease.

Product Specifications

CAS Number

9007-83-4

Specifications

Western blot: 1-2 µg/mL

UniProt

P09936

Host

Mouse

Reactivity

Human

Immunogen

Recombinant human protein was used as the immunogen for the UchL1 antibody.

Clonality

Monoclonal

Isotype

IgG2a κ

Clone

UCHL1/841

Applications

WB

Purity

Protein G affinity chromatography

Format

Purified

Buffer

0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide

Reconstitution

Store the UchL1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Limitations

This UchL1 antibody is available for research use only.

Storage Conditions

Store the UchL1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .

Formulation

0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide

Applications Notes

Optimal dilution of the UchL1 antibody should be determined by the researcher.

Location

Cytoplasmic, ER membrane

Image Legend

Western blot testing of human brain lysate with UchL1 antibody (clone UCHL1/841) . Predicted molecular weight ~25 kDa.

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