GRP94 Antibody / HSP90B1
Recognizes a protein of 94kDa, which is identified as the glucose-regulated protein 94 (grp94) and also tumor rejection antigen (gp96) . Grp94 shows a high degree of sequence homology with the heat shock protein 90 (hsp90) . This mAb is highly specific to grp94 and shows minimal cross-reaction with other members of the HSP90 family. Grps are a class of proteins unresponsive to heat shock and are induced by glucose deprivation. Grp94 has been briefly studied as a prognostic factor in breast cancer.
Product Specifications
CAS Number
9007-83-4
Specifications
Flow cytometry: 1-2ug/million cells, Immunofluorescence: 1-3 µg/mL, Western blot: 2-4 µg/mL, Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 min at RT
UniProt
P14625
Host
Rat
Reactivity
Human, Mouse, Rat
Immunogen
Purified glucose regulated protein 94 from chicken oviducts was used as the immunogen for the GRP94 antibody.
Clonality
Monoclonal
Isotype
IgG2a κ
Clone
9G10.F8.2
Applications
FACS, IF, WB, IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
1 mg/ml in 1X PBS; BSA free, sodium azide free
Reconstitution
Store the GRP94 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This GRP94 antibody is available for research use only.
Storage Conditions
Store the GRP94 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
1 mg/mL in 1X PBS; BSA free, sodium azide free
Location
Cytoplasmic and nuclear
Image Legend
Documents
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