CD43 Antibody
One of the major glycoproteins of thymocytes and T lymphocytes. Plays a role in the physicochemical properties of the T-cell surface and in lectin binding. Presents carbohydrate ligands to selectins. Has an extended rodlike structure that could protrude above the glycocalyx of the cell and allow multiple glycan chains to be accessible for binding. Is a counter-receptor for SN/Siglec-1 (By similarity) . During T-cell activation is actively removed from the T-cell-APC (antigen-presenting cell) contact site thus suggesting a negative regulatory role in adaptive immune response (By similarity) . [UniProt]
Product Specifications
CAS Number
9007-83-4
Specifications
UniProt
P16150
Host
Mouse
Reactivity
Human
Immunogen
Immature pluripotent human leukemia K562 cells were used as the immunogen for the CD43 antibody.
Clonality
Monoclonal
Isotype
IgM k
Clone
Bra7G
Applications
IHC-P
Purity
PEG precipitation
Format
Purified
Buffer
Prediluted in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide; *For IHC use only*
Reconstitution
Store the CD43 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This CD43 antibody is available for research use only.
Storage Conditions
Store the CD43 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
Prediluted in 1X PBS, 0.1 mg/mL BSA (US sourced), 0.05% sodium azide; *For IHC use only*
Location
Cell surface
Image Legend
IHC: Formalin-fixed, paraffin-embedded human spleen stained with CD43 antibody (clone Bra7G) .
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