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Fascin Antibody

Fascin organizes filamentous actin into bundles with a minimum of 4.1:1 actin/fascin ratio. Plays a role in the organization of actin filament bundles and the formation of microspikes, membrane ruffles, and stress fibers. Important for the formation of a diverse set of cell protrusions, such as filopodia, and for cell motility and migration. [UniProt]

Product Specifications

CAS Number

9007-83-4

Specifications

The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

UniProt

Q16658

Host

Mouse

Reactivity

Human

Immunogen

Full length recombinant human protein was used as the immunogen for the Fascin antibody.

Clonality

Monoclonal

Isotype

IgG2a κ

Clone

SPM133

Applications

IHC-P

Purity

Protein G affinity chromatography

Format

Purified

Buffer

Prediluted in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide; *For IHC use only*

Reconstitution

Store the Fascin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Limitations

This Fascin antibody is available for research use only.

Storage Conditions

Store the Fascin antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .

Formulation

Prediluted in 1X PBS, 0.1 mg/mL BSA (US sourced), 0.05% sodium azide; *For IHC use only*

Location

Cytoplasmic

Image Legend

IHC analysis of formalin-fixed, paraffin-embedded human Hodgkin's lymphoma stained with Fascin antibody (clone SPM133) .

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