ACTA2 Antibody Cocktail / Alpha Actin
Actin is a major component of the cytoskeleton and is present in most cell types. It is highly specific to actin from smooth muscles. This mAb does not stain cardiac or skeletal muscle; however, it does stain myofibroblasts and myoepithelial cells. This antibody could be used together with anti-muscle specific actin and myogenin in making a diagnosis of smooth muscle and skeletal muscle tumors. In most cases of rhabdomyosarcoma, this antibody yields negative results whereas anti-muscle specific actin and myogenin are positive. Leiomyosarcomas are positive only with anti-muscle specific actin and anti-smooth muscle actin and are negative with anti-myogenin.
Product Specifications
CAS Number
9007-83-4
Specifications
UniProt
P62736
Host
Mouse
Reactivity
Human, Rat
Immunogen
Clonality
Monoclonal
Isotype
IgG2a κ
Clone
1A4 + ACTA2/791
Applications
IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
Prediluted in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide; *For IHC use only*
Reconstitution
Store the ACTA2 antibody cocktail at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This ACTA2 antibody cocktail is available for research use only.
Storage Conditions
Store the ACTA2 antibody cocktail at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Product Datasheet
https://www.nsjbio.com/tds-pdf/acta2-antibody-cocktail-alpha-actin-1a4-acta2791-v2838
Formulation
Prediluted in 1X PBS, 0.1 mg/mL BSA (US sourced), 0.05% sodium azide; *For IHC use only*
Location
Cytoplasmic
Image Legend
IHC: Formalin-fixed, paraffin-embedded human leiomyosarcoma stained with ACTA2 antibody cocktail (clone 1A4 + ACTA2/791) .
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