NGFR Antibody
It recognizes a glycoprotein of 75kDa, identified as low affinity Nerve Growth Factor (NGF) Receptor (p75NGFR) or Neurotrophin Receptor (p75NTR) . NGFR is expressed in various neural crest cells and their tumors such as melanocytes, melanomas, neuroblastomas, pheochromocytomas and neurofibromas. Reportedly, anti-NGFR is a reliable marker for desmoplastic and neurotropic melanomas. NGFR is expressed in mature non-neural cells such as perivascular cells, dental pulp cells, lymphoidal follicular dendritic cells, basal epithelium of oral mucosa and hair follicles, prostate basal cells, and myoepithelial cells. Anti-NGFR stains the myoepithelial cells of breast ducts and intra-lobular fibroblasts of breast ducts.
Product Specifications
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 0.5-1 µg/mL for 30 min at RT
UniProt
P08138
Host
Mouse
Reactivity
Human
Immunogen
Recombinant human protein was used as the immunogen for the NGFR antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
NTR/912
Applications
IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Reconstitution
Store the NGFR antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This NGFR antibody is available for research use only.
Storage Conditions
Store the NGFR antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Location
Cell surface and cytoplasmic
Image Legend
IHC: Formalin-fixed, paraffin-embedded human melanoma stained with NGFR antibody (NTR/912) .
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Sh3bp5 sgRNA CRISPR/Cas9 All-in-One Lentivector (Rat) (Target 1)
LGMN (PRSC1, Legumain, Asparaginyl Endopeptidase, Protease, Cysteine 1) (MaxLight 490)
LGMN (PRSC1, Legumain, Asparaginyl Endopeptidase, Protease, Cysteine 1) (MaxLight 490)
NR1H3 Lentiviral Vector (Mouse) (CMV) (pLenti-GIII-CMV)