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Nucleolin Antibody

Recognizes a protein of ~76kDa, which is identified as Nucleolin (NCL). It is the major nucleolar phosphoprotein of growing eukaryotic cells. NCL is located mainly in dense fibrillar regions of the nucleolus. It is found associated with intranucleolar chromatin and pre-ribosomal particles. Human NCL gene consists of 14 exons with 13 introns and spans approximately 11kb. It induces chromatin decondensation by binding to histone H1. It is thought to play a role in pre-rRNA transcription and ribosome assembly.

Product Specifications

UniProt

P19338

Host

Mouse

Immunogen

Recombinant human protein was used as the immunogen for the Nucleolin antibody.

Clonality

Monoclonal

Isotype

IgG1 κ

Applications

FACS, IF, WB, IHC-P

Format

Purified

Buffer

1 mg/ml in 1X PBS; BSA free, sodium azide free

Reconstitution

Store the Nucleolin antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Limitations

This Nucleolin antibody is available for research use only.

CAS Number

9007-83-4

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