MUC5AC Antibody
This mAb recognizes the peptide core of gastric mucin M1 (recently identified as Mucin 5AC) . Its epitope is destroyed by beta-mercaptoethanol but not by periodate treatment. This mucin is present in primary ovarian mucinous cancer but usually absent in colorectal adenocarcinoma, thus showing an expression pattern opposite to MUC2. Together with a panel of antibodies, Anti-MUC5AC may be useful for differential identification of primary mucinous ovarian tumors from colon adenocarcinoma metastatic to the ovary. MUC5AC antibodies may also be useful for identification of intestinal metaplasia as well as in the identification of pancreatic carcinoma and pre-cancerous changes vs. normal pancreas.
Product Specifications
CAS Number
9007-83-4
Specifications
ELISA: 1-5 µg/mL for coating (order BSA/sodium azide-free format)
UniProt
P98088
Host
Mouse
Reactivity
Human
Immunogen
Clonality
Monoclonal
Isotype
IgG1 k
Clone
58M1
Applications
ELISA
Purity
Protein G affinity chromatography
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Reconstitution
Store the MUC5AC antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This MUC5AC antibody is available for research use only.
Storage Conditions
Store the MUC5AC antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Applications Notes
Optimal dilution of the MUC5AC antibody should be determined by the researcher.
Location
Cytoplasmic
Image Legend
SDS-PAGE analysis of purified, BSA-free MUC5AC antibody (clone 58M1) as confirmation of integrity and purity.
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