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NK-252

Product Specifications

UNSPSC Description

NK-252 is a potential Nrf2 activator, which exhibits a great Nrf2-activating potential.

Target Antigen

Keap1-Nrf2

Type

Reference compound

Related Pathways

NF-κB

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/NK-252.html

Purity

99.48

Solubility

DMSO : ≥ 29 mg/mL

Smiles

O=C(NCC1=NC=CC=C1)NC2=NN=C(C3=CC=CO3)O2

Molecular Weight

285.26

References & Citations

[1]Shimozono R et al. Nrf2 activators attenuate the progression of nonalcoholic steatohepatitis-related fibrosis in a dietary rat model. Mol Pharmacol. 2013 Jul, 84(1):62-70.|[2]Kiue A, et al. Enhancement of antitumour activity of etoposide by dihydropyridines on drug-sensitive and drug-resistant leukaemia in mice. Br J Cancer. 1991 Aug;64(2):221-6.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-19734/NK-252-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-19734/NK-252-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

1414963-82-8

Available Sizes

Curated Selection

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