NK-252
Product Specifications
UNSPSC Description
NK-252 is a potential Nrf2 activator, which exhibits a great Nrf2-activating potential.
Target Antigen
Keap1-Nrf2
Type
Reference compound
Related Pathways
NF-κB
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/NK-252.html
Purity
99.48
Solubility
DMSO : ≥ 29 mg/mL
Smiles
O=C(NCC1=NC=CC=C1)NC2=NN=C(C3=CC=CO3)O2
Molecular Weight
285.26
References & Citations
[1]Shimozono R et al. Nrf2 activators attenuate the progression of nonalcoholic steatohepatitis-related fibrosis in a dietary rat model. Mol Pharmacol. 2013 Jul, 84(1):62-70.|[2]Kiue A, et al. Enhancement of antitumour activity of etoposide by dihydropyridines on drug-sensitive and drug-resistant leukaemia in mice. Br J Cancer. 1991 Aug;64(2):221-6.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-19734/NK-252-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-19734/NK-252-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
1414963-82-8
Available Sizes
Curated Selection
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