Cytokeratin 7 Antibody
It recognizes an intermediate filament protein (IFP) of 55kDa, which is identified as cytokeratin 7. This MAb is highly specific to cytokeratin 7 and shows no cross-reaction with other IFPs. Cytokeratin 7 is a basic cytokeratin, which is found in most glandular and transitional epithelia but not in the stratified squamous epithelia. Keratin 7 is expressed in the epithelial cells of ovary, lung, and breast but not of colon, prostate, or gastrointestinal tract. This MAb is highly useful in distinguishing ovarian carcinomas (keratin 7+) from colon carcinomas (keratin 7-) .
Product Specifications
CAS Number
9007-83-4
Specifications
UniProt
P08729
Host
Mouse
Reactivity
Human
Immunogen
The ovarian carcinoma cell line OTN 11 was used as the immunogen for the Cytokeratin 7 antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
OV-TL12/30
Applications
FACS, IF, WB, IHC-P
Purity
Protein G affinity chromatography
Format
Biotin Conjugate
Buffer
0.1 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Store the Cytokeratin 7 antibody at 2-8oC (up to one month) or aliquot and store at -20oC (longer term).
Limitations
This Cytokeratin 7 antibody is available for research use only.
Storage Conditions
Store the Cytokeratin 7 antibody at 2-8°C (up to one month) or aliquot and store at -20°C (longer term) .
Formulation
0.1 mg/mL with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide
Applications Notes
Optimal dilution of the Cytokeratin 7 antibody should be determined by the researcher.
Location
Cytoplasmic
Image Legend
Frequently Asked Questions
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