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Anti-Tenascin C Antibody

Tenascin C is a multifunctional, disulfide-linked hexameric extracellular matrix glycoprotein expressed in association with mesenchymal epithelial interactions during development and in the neo-vasculature and stroma of undifferentiated tumors. In adults, it is restricted to certain epithelial-stromal interfaces and increases markedly in hyper-proliferative diseases and in stroma of many neoplasms, including gliomas, breast, squamous and lung carcinomas.

Product Specifications

CAS Number

9007-83-4

Specifications

Immunohistochemistry (FFPE) : 2-4 µg/mL for 30 min at RT

UniProt

P24821

Host

Mouse

Reactivity

Human

Immunogen

Human breast carcinoma cells were used as the immunogen for the anti-Tenascin C antibody.

Clonality

Monoclonal

Isotype

IgG1 k

Clone

SPM319

Applications

IHC-P

Purity

Protein G affinity chromatography

Format

Purified

Buffer

1 mg/ml in 1X PBS; BSA free, sodium azide free

Reconstitution

Store the anti-Tenascin C antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Limitations

This anti-Tenascin C antibody is available for research use only.

Storage Conditions

Store the anti-Tenascin C antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .

Formulation

1 mg/mL in 1X PBS; BSA free, sodium azide free

Location

Connective tissue matrix

Image Legend

IHC: Formalin-fixed, paraffin-embedded human lung carcinoma stained with anti-Tenascin C antibody (clone SPM319) at 4ug/ml.

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