HSP60 Antibody / HSPD1
Recognizes a 60kDa protein, identified as the heat shock protein 60 (HSP60) . A wide variety of environmental and pathophysiological stressful conditions trigger the synthesis of a family of proteins known as heat shock proteins (hsps), more appropriately called as stress response proteins (srps) . HSP60 is a potential antigen in a number of autoimmune diseases. In human arthritis and in experimentally induced arthritis in animals, disease development coincides with the development of immune reactivity directed against not only bacterial HSP60, but also against its mammalian homolog.
Product Specifications
CAS Number
9007-83-4
Specifications
Immunofluorescence: 1-2 µg/mL, Immunohistochemistry (FFPE) : 1-2 µg/mL
UniProt
P10809
Host
Mouse
Reactivity
Human
Immunogen
Recombinant human HSPD1 protein was used as the immunogen for the HSP60 antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
HSPD1/875
Applications
IF, IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Reconstitution
Store the HSP60 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This HSP60 antibody is available for research use only.
Storage Conditions
Store the HSP60 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Applications Notes
Optimal dilution of the HSP60 antibody should be determined by the researcher.
Location
Cytoplasm (mitochondria)
Image Legend
Immunofluorescent staining of MeOH-fixed human HeLa cells with HSP60 antibody (clone HSPD1/875, green) and Reddot nuclear stain (red) .
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