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HSP60 Antibody / HSPD1

Recognizes a 60kDa protein, identified as the heat shock protein 60 (hsp60) . A wide variety of environmental and pathophysiological stressful conditions trigger the synthesis of a family of proteins known as heat shock proteins (hsps), more appropriately called as stress response proteins (srps) . Hsp60 is a potential antigen in a number of autoimmune diseases. In human arthritis and in experimentally induced arthritis in animals, disease development coincides with the development of immune reactivity directed against not only bacterial hsp60, but also against its mammalian homolog.

Product Specifications

CAS Number

9007-83-4

Specifications

The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.

UniProt

P10809

Host

Mouse

Reactivity

Human

Immunogen

Recombinant human HSPD1 protein was used as the immunogen for the HSP60 antibody.

Clonality

Monoclonal

Isotype

IgG1 k

Clone

HSPD1/780

Applications

IHC-P

Purity

Protein G affinity chromatography

Format

Purified

Buffer

Prediluted in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide; *For IHC use only*

Reconstitution

Store the HSP60 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Limitations

This HSP60 antibody is available for research use only.

Storage Conditions

Store the HSP60 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .

Formulation

Prediluted in 1X PBS, 0.1 mg/mL BSA (US sourced), 0.05% sodium azide; *For IHC use only*

Location

Cytoplasm (mitochondria)

Image Legend

IHC: Formalin-fixed, paraffin-embedded human renal cell carcinoma stained with HSP60 antibody (clone HSPD1/780) .

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