HLA-ABC Antibody (MHC I)
Reacts with a monomorphic determinant of human major histocompatibility (MHC) class I antigens (HLA-A, B and C). Human MHC class I antigens are expressed constitutively on all nucleated cells lymphocytes such as lymphocytes, thymocytes, granulocytes, and bone marrow cells and are absent on erythrocytes. MHC class I antigens play a role in class I MHC-associated antigen presentation, inhibition of NK cell cytotoxicity, tumor surveillance, and tissue allotransplantation.
Product Specifications
UniProt
P30443, P01889, P30499
Host
Mouse
Immunogen
Human peripheral blood leukocytes were used as the immunogen for the HLA-ABC antibody.
Clonality
Monoclonal
Isotype
IgG2a κ
Applications
FACS, IF, WB
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Reconstitution
Store the HLA-ABC antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This HLA-ABC antibody is available for research use only.
CAS Number
9007-83-4
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