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Anti-CD57 Antibody

Anti-CD57 marks a subset of lymphocytes known as natural killer (NK) cells. Follicular center cell lymphomas often contain many NK cells within the neoplastic follicles. Anti-CD57 also stains neuroendocrine cells and their derived tumors, including carcinoid tumor and medulloblastoma. Anti-CD57 can also be useful in separating type B3 thymoma from thymic carcinoma when combined with a panel that includes antibodies against GLUT1, CD5, and CEA.

Product Specifications

CAS Number

9007-83-4

Specifications

Immunohistochemistry (FFPE) : 2-4 µg/mL for 30 min at RT

UniProt

Q9P2W7

Host

Mouse

Reactivity

Human

Immunogen

Human peripheral blood mononuclear cells were used as the immunogen for the anti-CD57 antibody.

Clonality

Monoclonal

Isotype

IgM k

Clone

SPM527

Applications

IHC-P

Purity

PEG precipitation

Format

Purified

Buffer

0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide

Reconstitution

Store the anti-CD57 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Limitations

This anti-CD57 antibody is available for research use only.

Storage Conditions

Store the anti-CD57 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .

Formulation

0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide

Location

Cell surface, cytoplasmic

Image Legend

IHC: Formalin-fixed, paraffin-embedded human tonsil stained with anti-CD57 antibody (SPM527) .

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