CD57 Antibody
Anti-CD57 marks a subset of lymphocytes known as natural killer (NK) cells. Follicular center cell lymphomas often contain many NK cells within the neoplastic follicles. Anti-CD57 also stains neuroendocrine cells and their derived tumors, including carcinoid tumor and medulloblastoma. Anti-CD57 can also be useful in separating type B3 thymoma from thymic carcinoma when combined with a panel that includes antibodies against GLUT1, CD5, and CEA.
Product Specifications
CAS Number
9007-83-4
Specifications
Immunofluorescence: 0.5-1 µg/mL, Immunohistochemistry (FFPE) : 2-4 µg/mL for 30 min at RT
UniProt
Q9P2W7
Host
Mouse
Reactivity
Human
Immunogen
Membrane antigen from HSB-2 cells was used as the immunogen for the CD57 antibody.
Clonality
Monoclonal
Isotype
IgM k
Clone
HNK-1 or Leu-7
Applications
IF, IHC-P
Purity
PEG precipitation
Format
Purified
Buffer
1 mg/ml in 1X PBS; BSA free, sodium azide free
Reconstitution
Store the CD57 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This CD57 antibody is available for research use only.
Storage Conditions
Store the CD57 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
1 mg/mL in 1X PBS; BSA free, sodium azide free
Location
Cell surface, cytoplasmic
Image Legend
IHC analysis of formalin-fixed, paraffin-embedded human tonsil stained with CD57 antibody (clone HNK-1) .
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