SSEA-1 Antibody Cocktail
SSEA-1/CD15 plays a role in mediating phagocytosis, bactericidal activity, and chemotaxis. It is present on >95% of granulocytes including neutrophils and eosinophils and to a lesser degree on monocytes. In addition, it is expressed in Reed-Sternberg cells and some epithelial cells. SSEA-1/CD15 antibody is very useful in the identification of Hodgkin s disease. CD15 is occasionally expressed in large cell lymphomas of both B and T phenotypes which otherwise have a quite distinct histological appearance.
Product Specifications
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 0.5-1 µg/mL for 30 min at RT
UniProt
P22083
Host
Mouse
Reactivity
Human, Mouse, Rat
Immunogen
Purified human neutrophils (FUT4/815) and Myelomonocytic leukemia cells (BRA-4F1) were used as the immunogen for the SSEA-1 antibody cocktail.
Clonality
Monoclonal
Isotype
IgM k
Clone
FUT4/815 + BRA-4F1
Applications
IHC-P
Purity
PEG precipitation
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Reconstitution
Store the SSEA-1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This SSEA-1 antibody is available for research use only.
Storage Conditions
Store the SSEA-1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Location
Cytoplasmic and cell surface
Image Legend
IHC: Formalin-fixed, paraffin-embedded human Hodgkin's lymphoma stained with SSEA-1 antibody (FUT4/815 + BRA-4F1) .
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