FSH-beta Antibody
This mAb reacts with a protein of 22 kDa, identified as beta sub-unit of FSH. It does not cross react with the alpha sub-unit. Follicle stimulating hormone (FSH) is a hormone synthesized and secreted by gonadotrophs in the anterior pituitary gland. In the ovary, FSH stimulates the growth of immature Graafian follicles to maturation. As the follicle grows, it releases inhibin, which deactivates the FSH production. In men, FSH enhances the production of androgen-binding protein by the Sertoli cells of the testis and is critical for spermatogenesis. FSH and LH act synergistically in reproduction. FSH is a useful marker in the classification of pituitary tumors and the study of pituitary disease.
Product Specifications
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 min at RT (1) (2)
UniProt
P01225
Host
Mouse
Reactivity
Human
Immunogen
Recombinant hFSH beta sub-unit was used as the immunogen for the FSH-beta antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
FSHb/1062
Applications
IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
0.2 mg/ml in 1X PBS with 0.1 mg/ml BSA (US sourced) and 0.05% sodium azide
Reconstitution
Store the FSH-beta antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This FSH-beta antibody is available for research use only.
Storage Conditions
Store the FSH-beta antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Location
Cytoplasmic, secreted
Image Legend
IHC: Formalin-fixed, paraffin-embedded human pituitary stained with FSH-beta antibody (clone FSHb/1062) .
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