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Semaphorin-4D Antibody / SEMA4D / CD100

Recognizes a homodimeric protein comprised of 50kDa subunits, identified as CD100. It is expressed on majority of haemopoietic cells (B, T, NK and myeloid cells) and is absent from bone marrow, erythrocytes, eosinophils and endothelial cells. Its expression is increased after PHA-activation. CD100 was shown to associate with different partner molecules in T cells such as CD45, a key molecule with protein tyrosine phosphatase activity involved in T-cell transduction, and a Serine kinase. It plays a role in homotypic cell adhesion and in T cell activation.

Product Specifications

CAS Number

9007-83-4

Specifications

Flow cytometry: 0.5-1ug/10^6 cells, Immunofluorescence: 0.5-1 µg/mL

UniProt

Q92854

Host

Mouse

Reactivity

Human

Immunogen

Human recombinant protein was used as the immunogen for the Semaphorin-4D antibody.

Clonality

Monoclonal

Isotype

IgG1 k

Clone

SEMA4D/933

Applications

FACS, IF

Purity

Protein G affinity chromatography

Format

Purified

Buffer

1 mg/ml in 1X PBS; BSA free, sodium azide free

Reconstitution

Store the Semaphorin-4D antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Limitations

This Semaphorin-4D antibody is available for research use only.

Storage Conditions

Store the Semaphorin-4D antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .

Formulation

1 mg/mL in 1X PBS; BSA free, sodium azide free

Location

Cell surface

Frequently Asked Questions

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