Anti-CEA Antibody / CEACAM5
CEA is synthesized during development in the fetal gut and is re-expressed in increased amounts in intestinal carcinomas and several other tumors. Antibody to CEA is useful in detecting early foci of gastric carcinoma and in distinguishing pulmonary adenocarcinomas (60-70% are CEA+) from pleural mesotheliomas (rarely or weakly CEA+) . Anti-CEA positivity is seen in adenocarcinomas from the lung, colon, stomach, esophagus, pancreas, gallbadder, urachus, salivary gland, ovary, and endocervix.
Product Specifications
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 min at RT
UniProt
P06731
Host
Mouse
Reactivity
Human
Immunogen
Human colon carcinoma extract was used as the immunogen for the anti-CEA antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
SPM506
Applications
IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
1 mg/ml in 1X PBS; BSA free, sodium azide free
Reconstitution
Store the anti-CEA antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This anti-CEA antibody is available for research use only.
Storage Conditions
Store the anti-CEA antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
1 mg/mL in 1X PBS; BSA free, sodium azide free
Location
Cytoplasmic and luminal surface
Image Legend
IHC: Formalin-fixed, paraffin-embedded human colon carcinoma stained with anti-CEA antibody (SPM506)
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