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PP65 Antibody / CMV-p65 / Cytomegalovirus

Ten to forty percent of the patients with acquired immunodeficiency syndrome (AIDS) develop cytomegalovirus (CMV) infections. In some patients with AIDS, cytomegalovirus is detected in the bronchoalveolar lavage fluid (BALF), urine, and other specimens, even when there are no symptoms of cytomegalovirus disease. An indicator of active CMV infection is needed to facilitate the diagnosis of cytomegalovirus disease in patients with AIDS or HIV infection. Cytomegalovirus p65 antigen was detected in the leukocytes of both the peripheral blood and BALF during the early phase of CMV disease.

Product Specifications

CAS Number

9007-83-4

Specifications

ELISA (order BSA/sodium azide-free format for coating), Immunofluorescence: 1-3 µg/mL

Host

Mouse

Reactivity

Cytomegalovirus

Immunogen

Recombinant Cytomegalovirus p65 protein was used as the immunogen for this PP65 antibody.

Clonality

Monoclonal

Isotype

IgG1 k

Clone

CMV101

Applications

ELISA, ICC, IF

Purity

Protein G affinity chromatography

Format

Purified

Buffer

1X PBS, pH 7.4

Reconstitution

Store the PP65 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Limitations

This PP65 antibody is available for research use only.

Storage Conditions

Store the PP65 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .

Formulation

0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide

Applications Notes

The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the PP65 antibody to be titered up or down for optimal performance.

Location

Nuclear

Image Legend

SDS-PAGE analysis of purified, BSA-free PP65 antibody (clone CMV101) as confirmation of integrity and purity.

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