FGF-23 Antibody / Fibroblast Growth Factor 23

Fibroblast growth factor-1 (FGF-1), also designated acidic FGF, and fibroblast growth factor-2 (FGF-2), also designated basic FGF, are members of a family of growth factors that stimulate proliferation of cells of mesenchymal, epithelial and neuroectodermal origin. Additional members of the family include the oncogenes FGF3 (Int2) and FGF4 (hst/Kaposi), FGF5, FGF6, FGF7 (KGF), FGF8 (AIGF), FGF9 (GAF) and FGF10 through FGF-23. Members of the family share 30-55% amino acid sequence identity and similar gene structure, and are capable of transforming cultured cells when overexpressed in trans- fected cells. Cellular receptors for FGFs are members of a second multigene family, including four tyrosine kinases designated Flg (FGFR-1), Bek (FGFR-L), TKF and FGFR-3.

Product Specifications

CAS Number

9007-83-4

Specifications

ELISA: order BSA/sodium azide-free format for coating, Functional studies: order BSA/sodium azide-free format

Host

Mouse

Reactivity

Human

Immunogen

A recombinant human FGF-23 protein was used as the immunogen for this antibody.

Clonality

Monoclonal

Isotype

IgG1 k

Clone

FGF23/638

Applications

ELISA, Functional studies

Purity

Protein G purified

Format

Purified

Buffer

1X PBS, pH 7.4

Reconstitution

Store the FGF-23 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Limitations

This FGF-23 antibody is available for research use only.

Storage Conditions

Store the FGF-23 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .

Formulation

0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide

Applications Notes

The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the FGF-23 antibody to be titered up or down for optimal performance.