FGF-23 Antibody / Fibroblast Growth Factor 23
Fibroblast growth factor-1 (FGF-1), also designated acidic FGF, and fibroblast growth factor-2 (FGF-2), also designated basic FGF, are members of a family of growth factors that stimulate proliferation of cells of mesenchymal, epithelial and neuroectodermal origin. Additional members of the family include the oncogenes FGF3 (Int2) and FGF4 (hst/Kaposi), FGF5, FGF6, FGF7 (KGF), FGF8 (AIGF), FGF9 (GAF) and FGF10 through FGF-23. Members of the family share 30-55% amino acid sequence identity and similar gene structure, and are capable of transforming cultured cells when overexpressed in trans- fected cells. Cellular receptors for FGFs are members of a second multigene family, including four tyrosine kinases designated Flg (FGFR-1), Bek (FGFR-L), TKF and FGFR-3.
Product Specifications
CAS Number
9007-83-4
Specifications
ELISA: order BSA/sodium azide-free format for coating, Functional studies: order BSA/sodium azide-free format
Host
Mouse
Reactivity
Human
Immunogen
A recombinant human FGF-23 protein was used as the immunogen for this antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
FGF23/638
Applications
ELISA, Functional studies
Purity
Protein G purified
Format
Purified
Buffer
1X PBS, pH 7.4
Reconstitution
Store the FGF-23 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This FGF-23 antibody is available for research use only.
Storage Conditions
Store the FGF-23 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Applications Notes
Image Legend
SDS-PAGE analysis of purified, BSA-free FGF-23 antibody (clone FGF23/638) as confirmation of integrity and purity.
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