CD98 Antibody / SLC3A2

CD98 exits as a heterodimer containing a disulphide-linked glycosylated heavy chain and a non-glycosylated light chain. It is a member of the solute carrier family and encodes a cell surface, transmembrane protein. The protein exists as the heavy chain of a heterodimer, covalently bound through disulfide bonds to one of several possible light chains. The encoded transporter plays a role in regulation of intracellular calcium levels and transports L-type amino acids. Alternatively spliced transcript variants, encoding different isoforms, have been characterized.

Product Specifications

CAS Number

9007-83-4

Specifications

Comitogenic with soluble anti-CD2 and immobilized anti-CD3 mAbs, Flow cytometry: 0.5-1ug/10^6 cells, Immunofluorescence: 0.5-1 µg/mL

Host

Mouse

Reactivity

Human

Immunogen

The Molt-13 T cell line was used as the immunogen for this CD98 antibody.

Clonality

Monoclonal

Isotype

IgG1 k

Clone

UM7F8

Applications

Functional studies, FACS, IF

Purity

Protein G purified CD98 antibody

Format

Purified

Buffer

1X PBS, pH 7.4

Reconstitution

Store the CD98 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Limitations

This CD98 antibody is available for research use only.

Storage Conditions

Store the CD98 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .

Formulation

0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide

Applications Notes

The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the CD98 antibody to be titered up or down for optimal performance.