CD45RB Antibody PE Conjugate
CD45R, also designated CD45 and PTPRC, has been identified as a transmembrane glycoprotein, broadly expressed among hematopoietic cells. Multiple isoforms of CD45R are distributed throughout the immune system according to cell type. These isoforms arise because of alternative splicing of exons 4, 5, and 6. The corresponding protein domains are characterized by the binding of monoclonal antibodies specific for CD45RA (exon 4), CD45RB (exon 5), CD45RC (exon 6) and CD45RO (exons 4 to 6 spliced out) . The variation in these isoforms is localized to the extracellular domain of CD45R, while the intracellular domain is conserved. CD45R functions as a phosphor-tyrosine phosphatase. antibody to CD45R is useful in differential diagnosis of lymphoid tumors from non-hematopoietic undifferentiated neoplasms.
Product Specifications
Specifications
Flow Cytometry: 5ul/test/10e6 cells in 100ul (or 5ul per 100ul of whole blood), Immunofluorescence: 1:50-1:100
Host
Mouse
Reactivity
Human
Immunogen
The non-T, non-B CALLA positive ALL cell line REH (Leucocyte Workshop IV and V) was used as the immunogen for this antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
BRA-11
Applications
FACS
Purity
Protein G affinity chromatography
Format
PE Conjugate
Buffer
500 ul at 0.1 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Store the CD45RB antibody at 2-8°C. Conjugate is light sensitive, store in the dark.
Limitations
This CD45RB antibody is available for research use only.
Storage Conditions
Store the CD45RB antibody at 2-8°C. Conjugate is light sensitive, store in the dark.
Product Datasheet
https://www.nsjbio.com/tds-pdf/cd45rb-antibody-pe-conjugate-bra-11-v2245pe
Formulation
500 ul at 0.1 mg/mL with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide
Applications Notes
CAS Number
9007-83-4
Location
Cell surface and cytoplasmic
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