Progesterone Receptor Antibody
This antibody is specific to progesterone receptor and shows minimal cross-reaction with other members of the family. Progesterone receptor is expressed as two major isoforms, PR-A (81kDa) and PR-B (116kDa) . Expression of progesterone receptor has been suggested to reflect a intact estrogen regulatory machinery and therefore predict better clinical response to endocrine therapy than ER alone.
Product Specifications
CAS Number
9007-83-4
Specifications
Immunohistochemistry (FFPE) : 0.5-1 µg/mL
Host
Mouse
Reactivity
Human
Immunogen
Recombinant human Progesterone Receptor protein was used as the immunogen for this antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
PR500
Applications
IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
1X PBS, pH 7.4
Reconstitution
Store the Progesterone receptor antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This Progesterone receptor antibody is available for research use only.
Storage Conditions
Store the Progesterone receptor antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Applications Notes
Location
Nuclear, cytoplasmic
Image Legend
IHC testing of human breast carcinoma stained with progesterone receptor antibody (PR500) .
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