Neurofilament Antibody / Heavy
Neurofilaments make up the main structural elements of axons and dendrites and are found in neurons, peripheral nerves, and sympathetic ganglion cells. Neurofilaments consist of three major subunits with molecular weights of 68kDa (NF-L), 160kDa (NF-M) and 200kDa (NF-H) . The fourth neurofilament subunit is alpha internexin in the central nervous system and peripherin in the peripheral nervous system.
Product Specifications
CAS Number
9007-83-4
Specifications
Host
Mouse
Reactivity
Human, Mouse, Rat
Immunogen
Human recombinant Neurofilament protein was used as the immunogen. (1)
Clonality
Monoclonal
Isotype
IgG1 k
Clone
NF421
Applications
IHC-P
Purity
Protein G purified Neurofilament antibody
Format
Purified
Buffer
1X PBS, pH 7.4
Reconstitution
Store the Neurofilament antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This Neurofilament antibody is available for research use only.
Storage Conditions
Store the Neurofilament antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
Prediluted in 1X PBS, 0.1 mg/mL BSA (US sourced), 0.05% sodium azide; *For IHC use only*
Location
Cytoplasmic, membranous
Image Legend
IHC testing of FFPE human cerebellum with Neurofilament antibody (clone NF421) .
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