CD11a Antibody / LFA-1
This antibody recognizes a protein of 180kDa, identified as CD11a. CD11a complexes with the beta 2 subunit of the integrin family, CD18, to form the cell surface heterodimer called LFA-1 or CD11a/CD18. LFA-1 is expressed on all leukocytes including lymphocytes, monocytes, and granulocytes. It is involved in leukocyte adhesion to its ligands including intercellular adhesion molecule-1 (ICAM-1 or CD54), ICAM-2 (CD102), ICAM-3 (CD50) and Telencephalin (TLN) and play a role in most immune/inflammatory responses.
Product Specifications
CAS Number
9007-83-4
Specifications
Flow cytometry: 1-2ug/10^6 cells, Immunofluorescence: 1-2 µg/mL Functional studies (order BSA/sodium azide-free format)
Host
Mouse
Reactivity
Human
Immunogen
Stimulated human leukocytes were used as the immunogen for this CD11b antibody.
Clonality
Monoclonal
Isotype
IgG2b κ
Clone
CRIS-3
Applications
FACS, IF Functional studies
Purity
Protein G affinity chromatography
Format
Purified
Buffer
1X PBS, pH 7.4
Reconstitution
Store the CD11a antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This CD11a antibody is available for research use only.
Storage Conditions
Store the CD11a antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Applications Notes
Location
Cell surface
Image Legend
FACS staining of human PBMCs using CD11a antibody (CRIS-3) .
Frequently Asked Questions
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