IgM Heavy Chain Antibody
This antibody recognizes a protein of 75kDa, identified as the mu heavy chain of human immunoglobulins. It does not cross-react with alpha (IgA), gamma (IgG), epsilon (IgE), or delta (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. The antibody is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. The most common feature of these malignancies is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.
Product Specifications
CAS Number
9007-83-4
Specifications
Flow cytometry: 5ul/test/10^6 cells in 0.1ml, Immunofluorescence: 1-2 µg/mL
Host
Mouse
Reactivity
Human
Immunogen
Recombinant heavy chain of human IgM was used as the immunogen for this antibody.
Clonality
Monoclonal
Isotype
IgG2b κ
Clone
IM373
Applications
FACS, IF
Purity
Protein G affinity chromatography
Format
CF488 Conjugate
Buffer
500 ul at 0.1 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Store the IgM Heavy Chain antibody at 2-8oC, protected from light.
Limitations
This IgM Heavy Chain antibody is available for research use only.
Storage Conditions
Store the IgM Heavy Chain antibody at 2-8°C, protected from light.
Formulation
500 ul at 0.1 mg/mL with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide
Applications Notes
Optimal dilution of the IgM Heavy Chain antibody should be determined by the researcher.
Location
Cytoplasm, Cell Surface and Secreted
Documents
Frequently Asked Questions
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