IgM Heavy Chain Antibody
This antibody recognizes a protein of 75kDa, identified as the mu heavy chain of human immunoglobulins. It does not cross-react with alpha (IgA), gamma (IgG), epsilon (IgE), or delta (IgD), heavy chains, T-cells, monocytes, granulocytes, or erythrocytes. The antibody is useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. The most common feature of these malignancies is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.
Product Specifications
CAS Number
9007-83-4
Specifications
Host
Mouse
Reactivity
Human
Immunogen
Recombinant heavy chain of human IgM was used as the immunogen for this antibody.
Clonality
Monoclonal
Isotype
IgG2b κ
Clone
IM373
Applications
FACS, IF, WB, IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
1X PBS, pH 7.4
Reconstitution
Store the IgM heavy chain antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This IgM heavy chain antibody is available for research use only.
Storage Conditions
Store the IgM heavy chain antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Location
Cytoplasm, Cell Surface and Secreted
Image Legend
IHC testing of human tonsil stained with IgM heavy chain antibody.
Documents
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