Secretory Component Antibody / ECM1
This antibody reacts with a reduction-resistant epitope present in both free and SIgA bound Secretory component. It does not react with the cell lines lacking this protein. The antibody is useful for studying the distribution and level of both free and bound secretory component. Secretory component is differentially expressed in epithelium, and the antibody is a popular marker for identifying subpopulations of epithelial cells and epithelial differentiation. The Secretory component antibody is a useful research tool for studying mucosal immunity, inflammation, remodeling, differentiation and tumorigenesis, all processes associated with differential secretory component expression.
Product Specifications
CAS Number
9007-83-4
Specifications
Flow cytometry: 0.5-1ug/10^6 cells, Immunofluorescence: 1-2 µg/mL, Immunohistochemistry (FFPE) : 0.5-1 µg/mL for 30 min at RT
UniProt
Q16610
Host
Mouse
Reactivity
Human, Rat
Immunogen
Secretory component protein isolated from human colostrum was used as the immunogen.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
SC05
Applications
FACS, IF, IHC-P
Purity
Protein G affinity chromatography
Format
Purified
Buffer
1X PBS, pH 7.4
Reconstitution
Store the Secretory Component antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This Secretory Component antibody is available for research use only.
Storage Conditions
Store the Secretory Component antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Product Datasheet
https://www.nsjbio.com/tds-pdf/secretory-component-antibody-ecm1-sc05-v2104
Formulation
0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05% sodium azide
Location
Cell surface and cytoplasmic
Image Legend
IHC testing of human colon carcinoma and Secretory Component antibody (SC05) .
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