CDK1 Antibody / CDC2
This antibody recognizes a 34kDa protein, which is identified as cyclin dependent kinase 1 (Cdk1) or p34cdc2 protein kinase. CDK1 plays a crucial role during cell division and is most active during mitosis. It is predominantly localized in the nucleus. It is a serine/threonine kinase, which is activated by cyclin, presumably by de-phosphorylation of tyrosine residues. Activated CDK1 performs specific functions during mitosis, including nuclear envelope breakdown and chromosome condensation.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 0.5-2 µg/mL, Immunohistochemistry (FFPE) : 2-4 µg/mL for 30 min at RT
UniProt
P06493
Host
Mouse
Reactivity
Human
Immunogen
Purified recombinant human Cdk1 / p34cdc2 was used as the immunogen for this CDK1 antibody.
Clonality
Monoclonal
Isotype
IgG2a κ
Clone
POH-1
Applications
WB, IHC-P
Purity
Protein G purified antibody
Format
Purified
Buffer
1X PBS, pH 7.4
Reconstitution
Store the CDK1 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This CDK1 antibody is available for research use only.
Storage Conditions
Store the CDK1 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
1 mg/mL in 1X PBS; BSA free, sodium azide free
Applications Notes
Location
Nuclear and Cytoplasmic
Image Legend
IHC testing of human tonsil stained with CDK1 antibody.
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