CD86 Antibody PE Conjugate
This antibody recognizes a protein of 70kDa, which is identified as CD86 (HLDA V; WS Code BP BP072. HLDA V; WS Code A A109. HLDA VI; WS Code BP 95. HLDA VI; WS Code B CD86.9) . CD86 is a type I transmembrane glycoprotein and a member of the immunoglobulin superfamily of cell surface receptors. It is expressed at high levels on resting peripheral monocytes and dendritic cells and at very low density on resting B and T lymphocytes. CD86 expression is rapidly upregulated by B cell specific stimuli with peak expression at 18 to 42 hours after stimulation. CD86, along with CD80/B71, is an important accessory molecule in T cell co-stimulation via its interaction with CD28 and CD152/CTLA4. Since CD86 has rapid kinetics of induction, it is believed to be the major CD28 ligand expressed early in the immune response. It is also found on malignant Hodgkin and Reed Sternberg (HRS) cells in Hodgkin's disease.
Product Specifications
CAS Number
9007-83-4
Specifications
Flow cytometry: 5ul/test/million cells, Immunofluorescence: 1:50-1:100
Host
Mouse
Reactivity
Human
Immunogen
ARH-77 (B-lymphoblastoid cell line) was used as the immunogen for this CD86 antibody PE conjugate.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
BU63
Applications
FACS, IF
Purity
Protein G affinity chromatography
Format
PE Conjugate
Buffer
500 ul at 0.1 mg/ml with 0.1 mg/ml BSA (US sourced), 0.05% sodium azide
Reconstitution
Store the CD86 antibody PE conjugate at 2-8oC. The conjugate is light-sensitive, protect from light.
Limitations
This CD86 antibody PE conjugate is available for research use only.
Storage Conditions
Store the CD86 antibody PE conjugate at 2-8°C. The conjugate is light-sensitive, protect from light.
Formulation
500 ul at 0.1 mg/mL with 0.1 mg/mL BSA (US sourced), 0.05% sodium azide
Applications Notes
Location
Cell surface
Image Legend
Unlabeled CD86 antibody (BU63)
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
