CD147 Antibody
This antibody recognizes extracellular epitope 2 within the N-terminal Ig domain of human CD147. It expressed more intensely on thymocytes than on mature peripheral blood T cells. CD147 is important in spermatogenesis, embryo implantation, neural network formation, and tumor progression. CD147 stimulates the production of interstitial collagenase, gelatinase A, stromelysin-1 and various metalloproteinases (MMPs) by fibroblasts. These enzymes are important factors in cancer invasion and metastasis.
Product Specifications
CAS Number
9007-83-4
Specifications
Western blot: 2-4 µg/mL, Flow cytometry: 1-2ug/million cells, Immunofluorescence: 1-3 µg/mL, Immunohistochemistry (FFPE) : 1-2 µg/mL for 30 min at RT
Host
Mouse
Reactivity
Human
Immunogen
Human T cell line Molt-13 was used as the immunogen for this CD147 antibody.
Clonality
Monoclonal
Isotype
IgG1 k
Clone
8D6
Applications
WB, FACS, IF, IHC-P
Purity
Protein G purified CD147 antibody
Format
Purified
Buffer
1X PBS, pH 7.4
Reconstitution
Store the CD147 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Limitations
This CD147 antibody is available for research use only.
Storage Conditions
Store the CD147 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide) .
Formulation
1 mg/mL in 1X PBS; BSA free, sodium azide free
Location
Cell surface, cytoplasmic
Image Legend
IHC testing of FFPE human renal cell carcinoma with CD147 antibody (clone 8D6) .
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